Analysis of extraocular muscle-infiltrating T cells in thyroid-associated ophthalmopathy (TAO)
نویسندگان
چکیده
منابع مشابه
T cells and fibroblasts in affected extraocular muscles in early and late thyroid associated ophthalmopathy.
AIM To determine whether there are differences in the lymphocytic cell infiltrate present in affected extraocular muscles (EOM) during early and late stages of thyroid associated ophthalmopathy (TAO). METHODS 17 biopsies of affected EOMs were collected from two groups of TAO patients (n=14): the first of five patients with early, active TAO, and the second of nine patients with late, inactive...
متن کامل[Evaluation of extraocular muscle enlargement in dysthyroid ophthalmopathy].
PURPOSE To evaluate the extraocular muscle enlargement in dysthyroid opthalmopathy. METHOD Extraocular muscle enlargement was assessed by orbital computed tomography (CT) in 573 patients with dysthyroid ophthalmopathy in order to investigate the frequency and exact location of extraocular muscle enlargement and the clinical features of related ocular symptoms in patients with dysthyroid ophth...
متن کاملThyroid-associated Ophthalmopathy
Thyroid-associated ophthalmopathy is the most frequent extrathyroidal involvement of Graves' disease but it sometimes occurs in euthyroid or hypothyroid patients. Thyroid-associated ophthalmopathy is an autoimmune disorder, but its pathogenesis is not completely understood. Autoimmunity against putative antigens shared by the thyroid and the orbit plays a role in the pathogenesis of disease. Th...
متن کاملExtraocular muscle enlargement with tendon involvement in thyroid-associated orbitopathy.
PURPOSE To evaluate the configuration of extraocular muscle and tendon enlargement in patients with thyroid-associated orbitopathy (TAO). DESIGN Retrospective, noncomparative case series. METHODS We retrospectively evaluated the preoperative computed tomography (CT) or magnetic resonance imaging (MRI) scans, or both, of 125 consecutive patients with previously diagnosed TAO. Axial CT (n = 8...
متن کاملGraves' ophthalmopathy: I. Simple CT estimates of extraocular muscle volume.
Graves' ophthalmopathy is an autoimmune inflammatory process affecting primarily the extraocular muscles. The enlargement of these muscles is responsible for most of the important manifestations of the disease, including proptosis, lid retraction, diplopia, and optic neuropathy. Recently the optic neuropathy has been shown to correlate with extraocular muscle volume as determined by computed to...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 1997
ISSN: 0009-9104
DOI: 10.1046/j.1365-2249.1997.4491347.x